I confess I have a fair bit of trouble attaching the word "worthy" to this sort of historico-teleological view-point -- and not merely due to Popper -- but I'll take your word for it. But, incidentally, I think that last item on your list should already by itself be counted as a powerful stab into the heart of Mr Fukuyama's thesis. It is fairly trivial to discover circumstantial evidence of human propensities towards whatever and whichever form of existence the theorist finds a fashionable topic of discussion in his circles at any particular time; it's an entirely different matter to sort out what such a notion as testing this particular kind of hypothesis should even mean in a historical framework. It's not as if the planet has a control group.