Of course Fukuyama is problematic but he does present a worthy argument with a historico-teleogical orientation from a liberal-democratic perspective. Such an orientation was almost entirely the domain of the Marxists for most of the twentieth century, to the point that liberal theorists actually started to argue against historical trajectories (e.g., Karl Popper's The Poverty of Historicism).

I think in order for historicism to be true there must be innate and universal in order for their to be telos and that it is possible to discern what those tendencies are, and that it is possible to test the hypothesis. Fukuyama, for example, would argue that there is an innate human desire towards liberalism and democracy - and a technical orientation that will result in transhumanism.